Dr.Siegall’s Contribution To Cancer Treatment Options

Seattle Genetics is a biotechnology company based in Seattle, Washington. It was co-founded in 1998 by Dr. Clay Siegall, who is the company’s current President and Chief Executive Officer. The goal of Seattle Genetics is to develop and commercialize monospecific antibodies that are made identical to immune cells in cancer. This form of treatment, commonly known as monoclonal antibody-based therapy can create clones of similar cells and bind to parts of an antigen that are recognized as an antibody. When this occurs, the monoclonal antibody is able to bind to that substance and purify it. The company is widely respected as the best in the industry for antibody-drug conjugates also known as ACD’s. More than 15,000 patients have benefited from the efforts of Seattle Genetics. In 2011 Seattle Genetics introduced ADCETRIS to the pharmaceutical market. This ADC is directed toward CD30, the protein that is expressed in Hodgkin lymphoma and systemic large cell lymphoma. In a 2010 clinical trial, and in several small studies the overall success rate of ADCETRIS was extremely significant. The FDA granted an accelerated approval for the drug on August 19, 2011 for relapsed patients. With the leadership of Dr.Siegall and the partnership with Takeda Pharmaceutical Company, ADCETRIS has become a global brand helping patients in more than 60 countries. Dr. Siegall founded Seattle genetics because of his true passion for helping patients. He has extensive training in science and cancer therapies, which is the foundation of his work at Seattle Genetics. Prior to Seattle Genetics, Dr. Siegall worked with the Bristol-Myers Squibb Pharmaceutical Research Institute and the National Cancer Institute. He has received a number of awards for his effortless contributions to the development of innovative cancer treatment options. http://www.xconomy.com/author/csiegall/ https://www.crunchbase.com/person/clay-b-siegall#/entity

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